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Sleep During Chronic Ethanol Administration and Withdrawal in Rats

Wallace B. Mendelson, Edward Majchrowicz, Nooreddin Mirmirani, Susan Dawson, J. Christian Gillin, Richard Jed Wyatt

SUMMARY. After a priming dose, ethanol was administered at a rate relative to behavioral impairment for 4 days and its effects on sleep were monitored by EEG. EEGs during withdrawal indicated an initial sleep loss followed by a return of total sleep and a REM sleep rebound several days later.