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Responses to Disulfiram in Healthy Young Men; a Double-Blind Study

David F. Silver, John A. Ewing, Beatrice A. Rouse, Robert A. Mueller

SUMMARY. Minimal changes in vital signs and subjective complaints occurred when healthy young men took disulfiram for 3 weeks at the usually prescribed dose; no inhibition of dopamine β-hydroxylase in peripheral blood could be demonstrated.