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An Atypical Neurocognitive Profile in Alcoholic Fathers and Their Sons

Stephen C. Whipple, Elizabeth S. Parker, Ernest P. Noble

Prepubescent boys and their recovering alcoholic fathers exhibited an Atypical Neurocognitive Profile consisting of ( 1 ) a reduction in amplitude of the late positive complex (LPC) of the event-related potential (ERP) during a complex visual discrimination task, and ( 2 ) reduced visuoperceptual performance evidenced by significantly lower scores on the Object Assembly, Block Design and Picture Completion subtests of the WISC-R and the Embedded Figures Test. Low LPC amplitudes were significantly correlated with poorer visuoperceptual performance. This Atypical Neurocognitive Profile may represent a marker for alcoholism.